Ocular Adverse Effects (OAES) of Molecularly Targeted Agents (MTAS) Approved in Oncology: A Systematic Review
نویسندگان
چکیده
منابع مشابه
Cardiotoxicity of Molecularly Targeted Agents
Cardiac toxicity of molecularly targeted cancer agents is increasingly recognized as a significant side effect of chemotherapy. These new potent therapies may not only affect the survival of cancer cells, but have the potential to adversely impact normal cardiac and vascular function. Unraveling the mechanisms by which these therapies affect the heart and vasculature is crucial for improving dr...
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Systemic anti-cancer therapies can produce acute and chronic organ damage. Ocular toxicity induced by anti-cancer chemotherapy is not uncommon, but underestimated and under-reported. The development of more aggressive regimens, use of newer agents and combination chemotherapies have resulted in a significant increase of reported cases of chemotherapies induced ocular side effects. Visual change...
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BACKGROUND This study defined the risk of serious toxicity in phase I trials of molecularly targeted agents (MTA). PATIENTS AND METHODS A retrospective analysis of toxicity data from patients treated in phase I trials of MTAs was carried out to define the rate of treatment-related grade 3/4 toxic effects, deaths and risk factors associated with grade 3 or more toxicity. RESULTS Data from 68...
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The use of transmission precautions such as contact isolation in patients known to be colonised or infected with multidrug-resistant organisms is recommended in healthcare institutions. Although essential for infection control, contact isolation has recently been associated with adverse effects in patients. We undertook a systematic review to determine whether contact isolation leads to psychol...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2012
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(20)34163-6